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The general picture emerging from these findings is that i) genes with high cell-cell variability in unstable silent chromatin are responsive to acute environmental changes and ii) genes whose expression is homogeneously maintained in stable silent chromatin respond to a prolonged or intensive stress that requires dramatic phenotypic changes such as cell fate transitions.
Breaking the habit of donation may also play a role, as habitual behaviours are easily maintained in stable circumstances but must return to more conscious control in the face of a novel situation [ 12].
Even modest losses of genetic diversity may result in a reduced ability to adapt to environmental change, yet the short-term impact of such losses may be minimal if populations are maintained in stable environments or if the loss does not cause detectable inbreeding depression-like effects.
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The learned songs are actively maintained in relatively stable form throughout adulthood [28], [29] when the sizes of song nuclei are also relatively stable [30].
The high current densities that were recorded by dc-voltammetry, however, could not be maintained in a stable way for a longer period.
The dimension of selector should be maintained in a stable range to optimize the grain orientation and select a single crystal efficiently.
In theory, alternative mating tactics may represent either distinct genetic alternatives, maintained in evolutionarily stable proportions, or conditional phenotype expression dependent on the environmentally determined state of the male.
However, the most likely explanation is that the managed population is maintained in a stable environment.
The genomic DNA of B-LCLs is maintained in a stable fashion.
Importantly, this predictive value was maintained in apparently stable hemodynamic conditions (defined as systolic blood pressure > 90 mmHg) [ 40, 41].
DOI: http://dx.doi.org/10.7554/eLife.03104.007 10.7554/eLiFigure04 figuregure 4—figure supplement 2. The input output transformation of individual cells is maintained in two stable states by complex mechanisms.
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