The superiority in ORR and PFS of the pom + loDex combination over hiDex was maintained in patients with moderate renal impairment, with a baseline creatinine clearance <60 mL/min, accordingly to Dr. Dimoupolos' communication at the last ASH meeting 2013 ASHH 2013, abstract number 2939).
Ionic liquids are non-aqueous salt solution that comprise both anions and cations which can be maintained in a liquid state at moderate temperatures (0 140 °C) [10, 11].
Organisms were maintained in nanopure water reconstituted to moderate hardness [ 86] and renewed weekly.
But it was clear that a convulsion in Israel, the West Bank or Gaza could threaten Washington's efforts to maintain support in moderate Arab countries, a problem that Mr. Bush's father faced in the 1991 coalition that defeated Iraq in Kuwait.
Studies showing that the stoichiometry among these proteins is tightly maintained in plants [ 41] and that moderate loss or overexpression of FtsZ, MinD and MinE impairs plastid division [ 11, 42, 43] suggest that normal plastid division requires the presence of the proper stoichiometric relationship among plastid division proteins.
Abilities assessed as part of the first factor were well maintained in individuals categorized with borderline or moderate dementia, as indicated by a total MMSE score of 15 or greater.
High levels of p16INK4a were maintained in these cells after reversal, whereas a moderate increase of p19ARF expression was detected in the same cell population (Fig. 5C).
Serial sacrifices conducted during the first 20 weeks following carcinogen exposure showed that metaplastic lung nodules, presumed to be precursors of later appearing carcinomas, occurred earlier and at higher incidence in rats maintained on low levels of RA than in rats maintained on moderate or high levels of RA.
Efficacy was maintained by moderate increases in dose (P<0.01) although absolute values were not reported.
At 16.5 dpc, Palm immunoreactivity is maintained at moderate levels in the cell bodies of both differentiating ganglion cells and undifferentiated neural precursors, but appears slightly stronger in the first morphologically distinguishable axons of the developing inner plexiform layer (ipl) which is composed of cell processes of the neurons of the inner nuclear layer and ganglion cells [ 50].
