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We analyzed to what extent the proteomic landscape of human colorectal cancer (CRC) is maintained in established CRC cell lines and the utility of proteomics for predicting therapeutic responses.
Furthermore, the significantly higher circulating levels of IL-6 and IL-22 were maintained in established RA.
Intact EBV plasmids can, however, be maintained in established cells under selection if they encode a drug resistance gene (Delecluse et al, 1998).
Because cancer cell lines are generally less heterogeneous than freshly isolated primary tumor cells and have the ability to grow indefinitely, in principle this property may not be maintained in established cell lines.
They were then sorted, coded and maintained in established files such as field files, mundane files and analytic files in an iterative process, comparing each interview with the previous interviews [ 4].
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Results: Challenges, many of them critical, were a regular occurrence: dealing with unforeseen obstacles, establishing and maintaining physician buy-in, establishing and maintaining staff buy-in, implementing the protocol as directed and with minimal intrusiveness, maintaining enthusiasm for the project over time, and knowing where (and where not) to allocate the Study's time, energy, and money.
As RAC1 permits the proliferation of LGR5 ISCs after Apc loss, we asked whether RAC1 is important for maintaining this population in established tumors.
The animals were housed and maintained in accordance with standards established in the Animal Welfare Act and the Guide for the Care and Use of Laboratory Animals.
An extensive network of lipid protein interactions mimicking native membranes is established and maintained in two-dimensional (2D) crystalline vesicles used for structural analysis by electron crystallography.
Both Hca-F and Hca-P cells were established and maintained in our laboratory [ 5, 6].
The hemoglobin concentration to be maintained in pregnancy has not been established.
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