Therefore, the use of current antibiotics could be maintained in their combination with plant-derived antibacterial agents as a therapeutic option in the treatment of S. aureus infections.
However, preliminary DL1-DL4 pharmacokinetic data showed a trend for a negative correlation between LPT dose and VNR clearance (see below), warranting the exploration of an immediate higher and approved LPT dose with the VNR dose used in DL3 in order to confirm potential pharmacokinetic interactions and to decide whether full dose anti-HER2 therapy could be maintained in the final combination.
Given the crucial role of these genes in latency establishment, it has been hypothesized that such acquisitions increased the virus' fitness as EBNA-2 and EBNA-3 blocks from type 1 and type 2 were maintained in the present combinations relative to a possible recombinant version between type 1 and type 2 (McGeoch 2001).
To exclude the possibility of this modification influencing the secretion properties as compared to the previously used 0.5ml apical, 1.5ml basolateral medium protocols [ 15], TER and PEDF secretion were measured in separate experiments of RPE Transwells maintained in apical/basolateral volume combinations of 0.5ml/0.5ml, 0.5ml/1.0ml, 0.5ml/1.5ml, 1.0ml/1.0ml incubation media.
This quiescent state is thought to be maintained in vivo by a combination of contact inhibition and antiproliferative autocrine and paracrine TGFβ signalling (Joyce, 2003).
In fact, as long as the linker peptide of GB2 is preserved, the activity of the dimer is maintained in a variety of chimeric combinations (Margeta-Mitrovic et al., 2001).
For example, Raymond et al. [ 10] reported that synergistic antiproliferative effects were observed when oxaliplatin was added to 5FU, and the synergistic effects of these combinations were maintained in the 5FU-resistant colon cancer cell line, HT29-5-FU.
On the other hand, the advantageous epistatic combination will be maintained in all future generations if the hybrid offspring backcrossed with the isolated population.
The τ value agreements were also maintained in the other tissue or rice variety combinations (Additional file 6: Figure S3).
Bending length (stiffness) of the sample was almost maintained in both the directions for all sets of finishing combinations.
