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hSNF5 was highly maintained in breast cancers, irrespective of RB1CC1 or p53 status (data not shown).
In this study, we demonstrate that PTHRP-R expression is indeed maintained in breast cancer BM.
Here, we addressed whether the functional relationship between cell growth and RUNX2 gene expression is maintained in breast cancer cells.
Our ongoing studies with breast tumors indicate that Frizzled-1, Frizzled-2 and Frizzled-6 expression is also maintained in breast tumors.
High resolution CGH analysis of breast cancer reveals several regions where DNA copy number is commonly gained or lost, that non-random correlations between specific amplicons exist, and that specific genetic alterations are maintained in breast cancer cell lines despite repeat passage in tissue culture.
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Unlike ER α, which is usually expressed in only a minority of cells in normal epithelium and aberrantly expressed at high levels in the majority of cells in many breast cancers, ER β1 is apparently expressed in the majority of cells in normal breast and this expression is maintained in most breast cancers at a variety of levels.
The present study showed that representative molecules contributing to establishment of cell polarity (junctional structures, domain identity and Rho family members), as well as MUC1 were well maintained in normal breast tissue, but disrupted by various degrees in human breast cancer subtypes.
We have also identified an autoregulatory feedback mechanism whereby CtBP protein abundance is maintained in proliferating breast cancer cells through the post-transcriptional regulation of CtBP2.
Thus, these results strongly argue for potent proapoptotic cooperation between GSIXII and ABT-737 in breast cancer cells maintained in their microenvironment.
The interconversion of tritium labelled oestrone and oestradiol-17β has been investigated in human breast tumours maintained in organ culture for 3 days.
We have recently demonstrated that this rhythmicity is roughly maintained in patients with bone metastatic breast cancer (Generali et al, 2007).
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CEO of Professional Science Editing for Scientists @ prosciediting.com