Exact(1)
Teleosts have experienced multiple gene losses and have only maintained duplicate paralogs in five HoxA genes and two to three HoxD genes.
Similar(59)
Alternatively, ancient genes with frequently maintained duplicates have gained essential functions.
Evolution of single-copy orthologs is also constrained at the sequence level and contrasts the elevated divergence among maintained duplicates.
With the exception of extremely recent polyploidy events, the majority of maintained duplicated loci are expected to be much older (have much higher divergence) than the alleles in a population, resulting in only a small number of duplicated loci exhibiting "confounding divergence".
This trend is consistent with studies that compared evolutionary rates of duplicated genes (with within-species homologs) with singletons (unique, without within-species homologs) and showed that conserved genes with constrained sequence evolution were more likely to give rise to maintained duplicates (Davis and Petrov 2004; Jordan et al. 2004).
Consideration should be given to maintaining duplicate records, disks, tapes, or microfilms.
There is a fear of duplicating efforts when it comes to digital preservation, but there is also a strong argument to be made for multiple, geographically dispersed entities maintaining duplicate preserved copies of important digital resources.
Consultants are offering for-fee advice on preparing for emergencies and telecommunications companies are reminding customers about the need for wireless communications systems, while operators of backup data sites are reminding clients of the importance of maintaining duplicate records at remote locations.
The relative ligand sensitivities of GR1 and GR2 in teleosts provide insight into the biological basis for maintaining duplicate GRs.
There are some cases of this technique being used, for example in India and in Swaziland, but there are serious logistic problems of maintaining duplicate seed stocks and of distributing them at the required time.
Naturally occurring Hsp70 gene duplicates experience extensive gene conversion, indicating selective pressure to maintain duplicate function [ 7], and increases in Hsp70 gene copy number in D. melanogaster can confer increased thermotolerance [ 6, 29].
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