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It is therefore plausible that these patients responded because their tumors maintained dependence on or addiction to the PI3K/AKT/mTOR axis despite the presence of additional gene alterations.
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Expression of hTERT (Fig. 1a) allowed for prolonged culture (and hence longer drug exposure time) while maintaining dependence on exogenous cytokines for differentiation and growth, which is a typical feature of the MUTZ3 cell line [ 16, 23].
The bill is likely to maintain our dependence on gas and will ensure we miss these targets.
For every dollar spent boosting renewables, nearly four dollars were spent to maintain our dependence on fossil fuels".
Their attitude is, 'The heck with it.' " There are also some business concerns oil companies, for example, he said that would prefer consumers to maintain their dependence on fossil fuels.
The mutations R177S and V198E restored the kanamycin resistance to wild-type levels while maintaining the dependence on leucine zippers for activity.
Over three orders of magnitude (0.1 100 ppb TC), the TRL signal maintains linear dependence on TC concentration; beyond 100 ppb filter effects becomes obvious.
The main driver behind carbon capture development is maintaining our dependence on fossil fuels.
When President Obama became the most recent American leader to lay out a plan for energy independence, he listed the perils of maintaining our dependence on imported oil: bankrolling dictators, paying for nuclear proliferation, funding terrorism..
Both acquired (BT474) and de novo (HCC1954) TRes cells, on the other hand, maintain their dependence on HER2, as evidenced by their sensitivity to lapatinib [ 13, 48] and the high levels of pEGFR, pHER2, and pHER3.
His alternative narrative focuses on the stories of successful African-American athletes who so wanted to be accepted by white society that they failed "to anticipate, plan and organize," maintained their "wholesale dependence on a racist white power structure," and showed "surprise and consternation when the money and support" were withdrawn.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com