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HCA also attenuated cellular injury and maintained cell membrane integrity, as evidenced by reduced concentrations of LDH, an intracellular enzyme which is released into the medium during cell disruption or necrosis.
When IκBα is directly overexpressed in the epithelial layers, it reduced stretch-induced NF-κB activation, decreased epithelial IL-8 production, maintained cell membrane integrity, and reduced stretch-induced cell death, demonstrating that these deleterious effects of cyclic stretch are mediated via NF-κB activation.
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Thus, 2 weeks after initiation of the carcinogenesis protocol, Cldn1-positive cells were decreased in the basal layer of the epidermis, while the entire suprabasal compartment maintained cell membrane-associated Cldn1 expression; by 4 weeks of treatment, the basal layer was essentially devoid of Cldn1.
The potential for HCA to attenuate stretch-induced inflammation, maintain cell membrane integrity, and enhance cell survival in HBE and BEAS-2B epithelial layers was then determined.
For long chain PUFAs, such as EPA and DHA, a major role in maintaining cell membrane fluidity is assumed (Nichols et al. 1993;Nishida and Murata 1996).
It has been postulated that microorganisms from polar regions contain relatively high (long chain) PUFA levels to maintain cell membrane fluidity (Nichols et al. 1993;Nishida and Murata 1996), but this was not confirmed by our study.
Our results demonstrate that DHA intake alters intrinsic and synaptic properties of EC deep layer neurons, maintains cell membrane surface area, ameliorates object recognition and reduces the number of seizure-like akinetic episodes observed in 3xTg-AD mice.
This suggests that ZFP252 protects plants from stress by maintaining cell membrane integrity.
This ZFP has been reported to confer drought tolerance in plants by maintaining cell membrane integrity during water stress.
Chronic lead exposure inhibits DNA transcription, vitamin D synthesis, and the function of enzymes that maintain cell membrane integrity.
It plays a major role in maintaining cell membrane integrity by limiting lipid peroxidation by ROS [ 22].
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