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These results proved that ERE-D20 maintained cell adhesion activity, even after fusion with D20.
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In contrast, this linkage appears critical for GPIb/V/IX to maintain cell adhesion under high shear and also for the ability of the cytoskeleton to exert negative regulatory effects on the GPIb-vWf interaction.
α-Catenin forms the link between the β-catenin/E-cadherin complex and the actin cytoskeleton, hence playing a key role in maintaining cell adhesion [53].
Here, the tumour suppressor CDH1 is responsible for maintaining cell adhesion and regulating cell migration.
FAK was much less expressed relative to control cells, but there were still small bright green spots, responsible for maintaining cell adhesion.
In its tumor suppressor role of maintaining cell adhesion integrity, methylation-mediated silencing of CDH13 would allow tumor cells to spread, facilitating metastasis and poorer survival.
We have identified a conserved protein and interactors required for maintaining cell adhesion during a simple collective migration in the developing C. elegans male gonad.
Serum deprivation was performed with 24 h incubation with medium containing 2% FBS followed by 2 h incubation with medium containing 0.5% FBS; 0.5% FBS was fed to maintain cell adhesion throughout every experimental period.
Even though the role of uPA/uPAR/integrin signalling in maintaining cell adhesion and proliferation has been described previously (Aguirre Ghiso et al, 1999b), our data for the first time establishes the role of this interaction in maintaining the invasive phenotype of colon cancer cells.
The ER Ca2+ is utilized to maintain cell adhesiveness by regulation of adhesion-specific proteins, such as fibronectin and vinculin, and by modulation of tyrosine phosphorylation cascades [5]; [6].
As expected, mock transfected BEAS-2B cells showed highly organized cell-to-cell adhesion and maintained cell polarity, which is the typical morphology of normal epithelial cells (Fig. 3).
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