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The mutant line was further maintained by mating between siblings.
The hemizygous SOD1G93A mice were maintained by mating transgenic males with wild-type (WT) females.
Breeding colonies were maintained by mating R26floxneoΔ256Foxo1 mice with AGRPCre mice.
The 129S8/SvEv strain is maintained by mating siblings.
The hemizygous line was maintained by mating transgenic males with C57BL/6 wild-type females.
Since the program began, both populations were managed as closed populations, maintained by mating approximately one male with three females.
Similar(42)
The ROP/GnLe strain (ROP- Os/+), was established at the Jackson Lab and has been maintained by sibling mating.
C57BL/6.Psl1dba congenic mouse strains were developed as previously described (Abel et al. 2010) and maintained by brother/sister mating.
All lines have been maintained by random mating within the flocks.
The line was then maintained by group mating of about 15 males and 30 females per generation.
From generation F3 onwards, about 100 birds per generation have been maintained by random mating and pedigree hatching up to generation F8.
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