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However, in around 15% of cancers, telomeres are maintained by alternative lengthening of telomeres (ALT) mechanisms (Henson et al. 2002).
These data suggest that in the absence of Dnhe2, pHi homeostasis during metamorphosis can be maintained by alternative ion transport mechanisms, changes in cellular buffering capacity and/or metabolic changes.
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In both mammalian tumor and yeast cells that lack telomerase, telomeres are maintained by an alternative recombination mechanism.
Once telomerase becomes completely dysfunctional, the gene encoding telomerase could be lost if telomeres are maintained by the ancestral alternative mechanism of homologous recombination.
It is generally assumed that telomeres are formed by T/G-rich minisatellites and maintained by telomerase until alternative telomere and maintenance mechanisms are shown for a given organism.
Telomere length in the remaining 15% of human cancers is maintained by the so-called alternative lengthening of telomeres (ALT) mechanism (Muntoni and Reddel 2005; Cesare and Reddel 2010).
The city (and the territory) are no more than an exercise field for various options maintained by different forces, often with alternative objectives; it is indeed due to the presence of opposed forces that the city, in general, and up to now, has never completely responded to the interests of one party.
It follows that unlike in the diploid case, cis-regulated alternative splicing cannot be maintained by selection alone, and that any observed polymorphism for alternative splicing should only be transient.
This is in keeping with the proposed model of cis-regulated alternative splicing we have developed, where alternative splicing is actively maintained by balancing selection (see below).
Our data are consistent with the suggestion that hummock grasslands and mulga shrubland are alternative stable states maintained by fire-soil feedback loops and possibly also by competitive exclusion of pyrophytic species by Acacia aneura.
It is likely therefore that loss of a requirement for apomictic msp occurred very recently (or that the sequences have alternative functions strongly maintained by selection).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com