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In the lumbar vertebrae and iliac crest, both doses of ODN prevented bone loss and maintained bone mass at a level comparable to intact animals.
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Such drugs relieve symptoms of menopause, like hot flashes, and can also help maintain bone mass.
"In this study, we show that leptin gene therapy causes effective long-term weight loss while maintaining bone mass".
Prime candidates have been a group of proteins called proteoglycans, which regulate the process of maintaining bone mass.
She led some of the first work on the role of weight-bearing exercise in building and maintaining bone mass and studied bisphosphonates as an osteoporosis treatment.
Given the importance of sex steroids for developing and maintaining bone mass, bone health is a matter of concern in daily management of these patients.
Load-induced fluid flow is a key factor in triggering bone modeling and remodeling processes that maintain bone mass and architecture.
The study shows that two factors important in maintaining bone mass in adult skeleton, estrogen and mechanical strain, act through a common pathway, says endocrinologist Lawrence Riggs of the Mayo Medical School in Rochester, Minnesota.
This is its role in maintaining bone mass and in preventing bone loss.
People with rheumatoid arthritis may be less active as a result of their pain, which means they do not exercise or stay active -- a key in maintaining bone mass.
Akt1 was established as a crucial regulator of osteoblasts and osteoclasts by promoting their differentiation and survival to maintain bone mass and turnover.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com