However, implementation usually maintains a subset of the total available paths in which preference is given to the optimal paths.
i.e ability to differentiate into different lineages under certain conditions, and ii) their ability to self-renew, i.e. maintain a subset of undifferentiated cells during differentiation.
Our data suggest that E/M-MP cells are able to differentiate into different lineages under certain conditions, and have the capacity for self-renewal, i.e. to maintain a subset of undifferentiated E/M-MP cells during differentiation.
For CF, the two genes in a WGD pair maintain exactly the same set of neighbors; in SF, each gene in a WGD pair maintains a subset of original neighbors, whereas the union of their neighbors equals the original set.
The high conservation of repeat element secondary structure suggests there is evolutionary pressure to maintain a subset of lipoprotein_1 genes/gene fragments with downstream sequences that can fold into a stem loop structure.
As development proceeds, many precursor cell types maintain a subset of developmentally critical genes in this conformation as well push new groups of cellular factors into a bivalent state.
However, as in aneuploid yeast, human aneuploid cells were also found to maintain a subset of proteins (enriched for complex subunits) at stoichiometric levels even if gene copy number was altered.
The top 15 downregulated genes include NTM, neurotrimin, encoding a protein that may promote neurite outgrowth and adhesion, PTK2B, protein tyrosine kinase 2 beta (also known as Pyk2), which functions in the activation of MAPK signaling pathways, and CTNNA2, catenin (cadherin-associated protein) alpha 2, expression of which is important for maintaining a subset of neurons.
Moreover, it is also implied that the overall fold of a protein may be mainly maintained by a subset of hydrophobic residues, as previously shown for molten globules, but the final formation of the native structure needs precise and specific packing also involved in hydrophilic residues [55] [68].
NeuroD is expressed in developing photoreceptors and is maintained in a subset of mature photoreceptors in the adult mouse retina.
