Sentence examples for maintained a chronic from inspiring English sources

These results do not necessarily contradict with the present study because the previous study maintained an acute diabetes condition and our present model maintained a chronic condition.

One subject, who acquired HBV infection at birth, did not respond to the primary vaccination course and maintained a chronic state throughout the long-term follow-up period.

The four cases who did not respond to the primary vaccination course in this study, maintained a chronic HBV infection status.

If the extent of DNA damage is irreparable, such a DDR becomes persistent so that distinct nuclear structures termed DNA-SCARS (DNA segments with chromatin alterations reinforcing senescence) form and the cell enters senescence but maintains a chronic, low level DDR (d'Adda di Fagagna, 2008; Rodier et al., 2011).

This highly sophisticated strategy of antigenic variation (reviewed in: [3], [4], [5]) allows the trypanosome to maintain a chronic infection.

Previous studies with B. abortus showed that SOD plays a role in establishing and maintaining a chronic infection in mice [11], [12].

We found fourteen proteins differently expressed in patients compared to controls, which could play an important role in either promoting or maintaining a chronic inflammatory state in subjects affected by SSc or ScGHVD.

It is also possible that increasing the level of SOD expression per se is insufficient to compensate for other critical genetic deficiencies of B. neotomae affecting its ability to maintain a chronic infection.

Stage specific expression of SRSs is important for parasite persistence and host immune evasion [6], for instance, four tandemly arranged genes encoding bradyzoite SRSs, SAG2CDXY, have been implicated in maintaining a chronic infection in the brain [7].

These findings suggest that B. neotomae can establish an acute infection in mice but it is unable to maintain a chronic infection like other known virulent Brucella spp. This characteristic feature makes B. neotomae an attractive candidate to be included in studies to understand the mechanisms employed by virulent Brucella spp. in causing chronic infections in mouse models.

However, at 3 weeks post-infection, there was a 3 log decrease in the bacterial burden in the spleens and no bacteria were recovered from the livers, indicating the inability of these bacteria to maintain a chronic infection (Fig. 10A & B).