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These results demonstrate that the laminin extracellular matrix plays multiple critical roles regulating adhesion and polarity to establish and maintain tissue structure during optic cup morphogenesis.
To identify genes and pathways that maintain tissue structure and function in old age, new approaches for quantifying tissue morphology are needed.
Linking differentiation to cell cycle progression might contribute to maintain tissue structure, even upon molecular alterations that otherwise would be oncogenic.
What is not understood is how a slight increase in temperature (20°C to 25°C, which is not typically thought of as a stressful environment for C. elegans) or a change in equally accepted laboratory food sources influence an animal's ability to maintain tissue structure and/or function (an unimpaired versus an impaired phenotype) after anoxia treatment.
Aging is associated with a declining ability to maintain tissue structure and function.
This finding suggests that regulatory mechanisms are in place to sense cell size and adjust cell morphology accordingly in order to maintain tissue structure [ 134].
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For instance, it does not explain how skin maintains tissue structure in hyperproliferative benign lesions.
Most of the cells are surrounded by a highly complex ECM that is important in maintaining tissue structure but also plays key roles in guiding cell function.
Further, the collagen type I maintaining tissue structure and collagen type IV, a component of basal lamina that allows interaction with integrins and favors cell adhesion, were increased expressed.
In addition to anchoring cells to matrix fibres and maintaining tissue structure, HSPGs serve at least two additional biological activities.
ASCs are primarily responsible for maintaining tissue structure; they accomplish this through their functional duality between self-renewal and commitment.
More suggestions(15)
maintain granuloma structure
maintain chromosome structure
maintain tissue oxygen
maintain tissue viscoelasticity
maintain domain structure
maintain tissue perfusion
maintain tissue contact
maintain cluster structure
maintain tissue stiffness
maintain tissue oxygenation
maintain soil structure
maintain tissue carnitine
maintain skin structure
maintain tissue hydration
maintain tissue architecture
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