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The Barrx system requires flat epithelium to maintain tissue contact and complete uniform ablation [ 28].
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This model more closely reflects the in vivo joint environment, as it maintains tissue architecture and cell-cell contact of the complex mix of different cell types whose interaction contributes to the pro-inflammatory environment in the RA joint.
It also maintains tissue donation is a completely routine and legal part of medical practice.
We have previously identified a highly viscoelastic material on days 2 and 4 of adipocyte differentiation resembling extracellular matrix components secreted by preadipocytes to maintain adipose tissue cell-cell contact, morphological induction of adipocytes and functional and gene expression indicative of mature adipocyte lineage.
While this allowed the volunteer to maintain good contact with the lip tissue and apply a more consistent pressure throughout measurements, this does not replicate the clinical scenario in which a physician uses the probe on a patient.
To maintain good contact and eliminate gaps between the probe and tissue interface a gentle pressure is usually applied to these probes.
You have to maintain eye contact.
They can't maintain eye contact with you.
But there is no requirement that they maintain continuous contact.
Can't maintain eye contact.
It allows you to maintain eye contact with the audience".
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