Sentence examples for maintain these cells from inspiring English sources

IL-15 prevents the suppressive effect of Tregs on T cells24, whereas IL-2 is required to maintain these cells (CD4+CD25+ 19.

"Our data provide evidence that peripheral nerve injury changes the landscape of microglial enhancers — a process that could maintain these cells in an abnormal, maladaptive state," the scientists report.

Here, we report the development of an immunopanning method to acutely purify astrocytes from fetal, juvenile, and adult human brains and to maintain these cells in serum-free cultures.

She said: "The next important challenge will be to find ways to maintain these cells inside the body so they are protected from the immune response and have long-term function".

To maintain these cells in culture, they were immortalized by retrovirus-mediated transduction with the v-myc gene.

However, the low frequency of CSCs in primary tumours and the difficulty to stably maintain these cells in vitro makes some of these systems difficult to use.

The media used to maintain these cell lines did not contain any vitamin C in their formulas.

IL-7 plays an essential role in lymphocyte homeostasis as it favours T cell proliferation while maintaining these cells in their maturation stage49.

The donor T cells exhibited the expected Th1 phenotype, i.e. IFNγ+TNFα+IL2+Foxp3− (Fig. 5A), and had regained IL-7Rα expression at the time of transfer (Fig. 5B). Figure 5C shows that rhIL-7 administration not only boosted the expansion of the infused Th1 cells but also maintained these cells at higher levels for a sustained period compared to the control group.

GSEA reveals a stem cell signature amongst the direct Myc up-regulated genes, suggesting the Myc maintains these cells in an undifferentiated stem cell-like state.

The DTC produces the Notch ligand LAG-2 [47] [49], which activates the GLP-1/Notch receptor in nearby germ cells and maintains these cells in the undifferentiated (mitotic) state [50], [51].