Sentence examples for maintain therapeutic levels from inspiring English sources

Point-of-care devices for measurement of the international normalized ratio (INR) are commonly used to monitor therapy and maintain therapeutic levels of anticoagulation in patients treated with vitamin K antagonists.

The use of polymers is designed to maintain therapeutic levels of the drug, to reduce the side-effect profile, to decrease the amount of drug molecule and the dosage frequency, and to facilitate the delivery of drugs with short in vivo half-lives.

No noticeable side-effects were observed when antiepileptic doses were raised to maintain therapeutic levels along the evolution of the disease due to the patient increasing weight.

Third, effective therapeutic use of anticoagulation requires regular blood monitoring of the international normalised ratio (INR) and dose titration to maintain therapeutic levels (2.0 3.0) [ 13].

This may lead to a marked decrease in plasma concentration of these drugs; therefore in order to maintain therapeutic levels dose adjustment may need to be done when starting and stopping rifampicin.

107, 108 This suggests that at higher doses, the drug is able to reach higher concentrations and even with equivalent excretion rates, maintain therapeutic levels for an extended period of time.

The current challenge for the clinical applications of gene modified cells is enhancing the safety of gene delivery vectors while maintaining therapeutic levels of transgene expression.

Edoxaban could be an excellent alternative for stroke prevention in NVAF patients who are either intolerant to warfarin or have difficulty in maintaining therapeutic levels due to dietary or medication interactions.

Table  2 provide the details pertaining to seven clinics utilized by 3 or more patients for INR monitoring, indicating the number of patients who maintained therapeutic levels according to whether or not they had had a MVRs.

Recent data from our laboratory have shown that the synovial lining is capable of maintaining therapeutic levels of transgene expression for at least 6 months [ 28], providing increased optimism for the use of gene transfer in the treatment of chronic articular disease.

In two retrospective studies in which data were collected from kidney transplant patients converted from reference to generic tacrolimus (Sandoz), involving 45 patients (27) and 75 patients (28), respectively, the tacrolimus dose required to maintain therapeutic trough levels was similar with both preparations (27) and trough levels were maintained (27, 28).