Sentence examples for maintain their proliferative from inspiring English sources
In contrast, 3D culture provides a microenvironment in which the cells maintain their proliferative potential.
Accordingly, they recently demonstrated that ΔNp63 is required for adult epithelial stem cells to maintain their proliferative potential [6].
Tissue engineering requires understanding how normal tissues arise, develop, renew themselves, and maintain their proliferative quiescence and homeostasis.
One might hypothesise that NA precursor cells bypass their normal progression to terminal differentiation but instead maintain their proliferative potential for an extended period of time.
Although these T cells maintain their proliferative and cytolytic capacity 7, this enhanced frequency that dominates the global T-cell repertoire is associated with impaired T-cell responsiveness to heterologous antigens 8.
Sympathetic progenitor cells are known to maintain their proliferative potential while expressing NA markers such as Ascl1, Phox2a, Hand2 and TH (Ernsberger et al., 1989; Rohrer, 2011), although we observed decreased expression of these markers on CDK hyperactivation (Fig. 6).
The proliferation curve of pN1 and pD2 cells shows that our mdcs maintained their proliferative capacity until 30 mpds before entering into senenscence (figure 1b), slightly longer than reported for pericytes (20 25 mpds) [13].
Examining wound healing in mice with the same gain of function mutation in LRP5, Kim and colleagues showed that at the injury site osteoprogenitor cells maintained their proliferative state and have delayed osteoblastic differentiation resulting in an 84% reduction in injury-induced bone regeneration compared with controls [56].
EdU incorporation confirmed that the cells maintained their proliferative state in vitro for >3 months.
This study demonstrated that human cells maintained their proliferative capacity after the 10th passage.
Transformed prostate epithelial (TPE) and prostate cancer (PCa) cells express both MCT1 and MCT4 and demonstrated variable dependence on aerobic glycolysis for maintaining their proliferative rate.
