Sentence examples for maintain their phenotypes from inspiring English sources
Consequently, the hybridization of fibrin and PLCL scaffolds for three-dimensional spatial organization of cells and the effective delivery of TGF-β1 using heparin-functionalized nanoparticles can induce hASCs to differentiate to a chondrogenic lineage and maintain their phenotypes.
The in vivo results show that chondrocytes can proliferate and maintain their phenotypes in the hydrogel, with the production of abundant extracellular matrix (ECM) components, formation of typical chondrocyte lacunae structure and increase in Young's modulus over 12 weeks, as indicated by histological, immunohistochemistry, gene expression analyses and mechanical test.
However, since chondrocytes uniquely maintain their phenotypes in 3-dimensional cultures [ 37], it is not known whether hTERT-immortalized chondrocytes maintain their state of differentiation.
It was important to ensure that EBN besides inducing proliferation of corneal cells was also capable to maintain their phenotypes and functionality by synthesizing and organizing stromal constituents crucial in maintaining corneal transparency.
We examined whether cells sorted for positive or negative expression, or whether the putative stem cell makers maintain their phenotypes when grown as monolayers in conventional tissue culture dishes.
Tissue engineering and cell based liver therapies have utilized primary hepatocytes with limited success due to the failure of hepatocytes to maintain their phenotype in vitro.
Results of the in vitro osteocompatibility evaluation demonstrated that cells adhere, proliferate, and maintain their phenotype when seeded directly on the surface of PNEA, PNEA50mPh50, and PNEA50PhPh50.
The results indicated that, after osteogenic differentiation, AFSCs that had been seeded onto SPCL scaffolds did not require osteochondral medium to maintain their phenotype, and they produced a protein-rich, mineralized extracellular matrix (ECM) for up to 2 weeks.
Chondrocytes delivered in the more electropositive MAX8 gel experienced a greater degree of cell death during encapsulation and delivery and the remaining viable cells were less prone to maintain their phenotype.
Various approaches have been utilized to design in vitro hepatocyte cultures in order to maintain their phenotype.
Our data complement and extend previous findings on human skeletal muscle-derived stem cells, and clearly indicate that further work is necessary to prepare pure cell populations from skeletal muscle that maintain their phenotype in culture and make a robust contribution to skeletal muscle regeneration after systemic delivery in dystrophic mouse models.
