Sentence examples for maintain their differentiated from inspiring English sources
In vitro analysis showed that both SC and MSC adhered significantly better to PHB in the presence of fibrin and cells continued to maintain their differentiated state.
We also developed an advanced macroporous and nanofibrous (NF) poly l-lactic acid) (poly l-lacticd with suitacid PLLA scaffold interpore connectivity to seed these human iPSC-derived SMCs and maintain their differentiated phenotype.
Some data suggest that oncogenic mutations lead to loss of the ability for cells to maintain their differentiated state.
Thus, the levels of ZO-1 and ZONAB expression are important determinants of RPE cell morphology and differentiation in vivo, indicating that ZO-1 and ZONAB are critical for RPE cells to maintain their differentiated phenotype and to fulfil their support function for the neural retina.
Previous studies indicated that chondrocytes can maintain their differentiated phenotype for up to four passages in monolayer culture [ 13, 14].
These studies show how a mechanistic understanding of transcription factor engagement with chromatin reveals features by which cells stably maintain their differentiated states.
Notch3 also feeds back and promotes Jagged1 expression in pericytes, thereby maintaining their differentiated state [ 55].
However, since the different protocols are in practical use we have maintained their differentiated profile for reference.
When sorted and plated separately, 5 to 10% of the CD49f+/EpCAM-/low SUM149PT cells differentiated into CD49f+/high/EpCAM+ basal-like cells, whereas the CD49f+/high/EpCAM+ basal-like cells maintained their differentiated status during in vitro culture.
Prompted by these transcriptomic findings, we wished to explore further the possibility that BAP1 inhibits metastasis of uveal melanoma cells by maintaining their differentiated state and impeding their reversion to a stem-like state.
Analysis of these mice demonstrated that cells that were marked upon induction of InsII (also known as Ins2) expression faithfully maintained their differentiated phenotype, even when some of these cells co-expressed other endocrine hormone genes.
