Sentence examples for maintain the apical from inspiring English sources
We propose that this reflects its role in the apical exclusion of Baz to maintain the apical domain during junctional remodeling.
The maternal pool of Baz runs out at this stage, however, and the epithelia become disorganized and fail to maintain the apical localization of aPKC.
Vesicular trafficking to the tip region is a structural requirement for tip growth and plays a significant role in feedback regulation of the tip-localized signaling to maintain the apical cell expansion [ 10].
Professor Rescigno discussed an ex vivo organ model system developed by her group, which involves a human mucosa explant onto which a cylinder is applied, without damaging the cells, to maintain the apical to basolateral polarity of the tissue.
These data suggested that the mutant radial glial progenitors were able to establish apical junctions and overall polarity, but fail to maintain the apical cell shape and intimate association with apical ventricular surface during mitosis.
During embryogenesis, NBs delaminate from a neuroepithelium and maintain the apical-basal polarity of this epithelium.
Thus, some other molecule(s) must be generally responsible for maintaining the apical endfoot in the rodent cortex.
Kv1.1 K+ channel maintains the apical transmembrane voltage, thought to be the driving force behind Mg2+ reabsorption via TRPM6 in the distal convoluted tubule.
Thus, our finding on Lis1 Nde1's role in maintaining the apical morphology of bi-polar VZ progenitors reconciles the conflicting observations on the mitotic spindle regulation of the neurogenic cell fate.
Therefore, Lis1 Nde1 is not only essential for mitotic orientation determination, but also critically required for maintaining the apical integrity and lateral contacts of radial glial neural or neuroepithelial progenitors during mitosis (Fig. 9).
They arise from a polarized epithelium from which they delaminate while maintaining the apical localization of the so-called Par complex, consisting of the adaptor proteins Bazooka (Baz Drosophilaa homolog of Par-3), Par-6, and the protein kinase aPKC (Suzuki and Ohno, 2006).
