The multifaceted nature of medication adherence, due to a large number of underlying factors, presents several critical challenges including how to evaluate the current level of adherence, how to improve and how to maintain the required level of medication adherence, especially for long-term chronic conditions.
In order to minimize exposure to the host immune system and at the same time maintain its adherence properties, expression of the protein is epigenetically regulated such that only one copy of the encoding var gene repertoire is active per parasite at a given time, while the remaining approximately 60 variants are transcriptionally silent.
To reduce participant drop out and to maintain adherence to the training program, the potential benefits of performing the training will be explained to subjects in the intervention group.
This is despite the participants being contacted by telephone at a number of intervals by the researchers to promote adherence to the program, indicating that further strategies are required to maintain adherence over the longer term.
Duration may be a function of power relationships: a dominant coalition member or set of members may be able to either dissolve the coalition or maintain ongoing adherence.
Respondents perceived monitoring combined with feedback activities as an effective activity to motivate, remind and encourage staff to maintain adherence to the ERAS programme.
In such case there is a need to develop skill to maintain adherence in the non-disclosure state or design a way to encourage for disclosure.
To reduce participants drop out and to maintain adherence to the training program, all sessions will be accompanied with music [ 43], and will be performed on an airy, well lighted exercise room.
Moreover, the provision of basic pharmaceutical care and adverse event management was sufficient to maintain adherence in initially adherent patients for at least six cycles.
The findings highlight the need for more effective interventions to maintain high adherence over time.
