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Very recently, another homolog of SDG724, OsTrx1, which belongs to SET domain family Class III (Ng et al., 2007), might activate or maintain the active transcribed states of target genes, and was reported to delay flowering time under LD through Ghd7 pathway but not OsMADS50 and Hd1 pathways (Choi et al., 2014).
This result suggests that phosphorylation serves as a trigger for the activation process but is not essential to maintain the active state.
Its mammalian ortholog, RACK1 was initially discovered as a receptor for activated protein C kinase (PKC) that functions to maintain the active conformation of PKC and to support its movement to target sites.
FRRs are typically activated (manually or automatically) within 15 min, in order to maintain the active power balance in the power system and the power exchange with neighbouring power system on its schedule.
The TSOs have to maintain the active power in balance in any operating condition.
Consequently, helix αC is "pulled in" to maintain the active orientation, and the usual pre-existing hydrophobic back pocket of the ATP-binding site is abolished.
Similar(32)
For example, RACK1 stabilizes the activity of protein phosphatase 2A (PP2A) [ 58, 59] and maintains the active conformation of PKCβII [ 42, 45, 60].
Deletion of the "LLWL" motif abrogated the proteolytic activity, indicating that the motif is critical for maintaining the active proteinase conformation.
Handoff management maintains the active connections for roaming mobile terminals as they change their points of attachment to the network.
Our results also reveal the significant loop residues in maintaining the active binding conformation in the HD32D228 model.
Thus, the majority of interactions mediated by the studied amino-acid residues seem to play important role in maintaining the active conformation.
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