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Epistasis was suggested to contribute to viral robustness, the ability of a virus to maintain stable functioning despite genetic and environmental perturbations [1], [25].
Robustness is a fundamental property of biological systems and is defined as the ability to maintain stable functioning in the face of various perturbations.
Cancers are extremely complex systems that possess many features of robustness, i.e., they are systems that tend to maintain stable functioning despite various perturbations [ 1, 2].
Tumor heterogeneity provides a high degree of redundancy and contributes to acquired tumor "robustness," that is, the ability to maintain stable functioning despite various perturbations (8).
Robustness, a fundamental and ubiquitously observed phenomenon in biological systems, is defined as the ability to maintain stable functioning in the face of various perturbations, and is characterized as genetic or environmental robustness, depending on whether the perturbations are inheritable or not [ 1].
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Such neural circuits must maintain stable function in the face of many plastic challenges during learning, development and aging.
Postoperative 99mTc-pertechnetate examination showed that the secretory function from all viable transplanted SMGs maintained stable function in the long term [21].
The reports from these groups confirmed that the secretions from all viable transplanted SMGs maintained stable function in the long term and had been effective for severe cases of KCS [12-17].
Compared with standard care, the intervention helped carers maintain stable mental functioning and improved their sense of mastery.
Pathway structures, with redundancy and feedback to maintain stable organismal functions, may also impact the therapeutic effect of target drugs.
However, not all ABMR phenotypes have poor outcomes, and many patients maintain stable graft function for years after treatment of the initial injury.
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maintain independent functioning
maintain physical functioning
maintain natural functioning
maintain normal functioning
maintain stable expression
maintain optimal functioning
maintain stable physiology
maintain stable employment
maintain physiological functioning
maintain psychosocial functioning
maintain stable superelasticity
maintain stable viscosity
maintain stable network
maintain stable superhydrophobicity
maintain stable glutamate
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