The inclusion of hospital records showing the discharge status as in-hospital death (S1) produced the highest sensitivity (99.8%) and NPV (100.0%) while maintaining specificity and PPV.
These binding sites maintain specificity by means of their sequence, and other additional factors such as inter-motif distance and spacer specificity.
The plant VDAC motif detected 43 sequences in the public databases, and anchoring to the N-terminus was not necessary to maintain specificity.
The 3.5 score threshold was used to maintain specificity, although at the cost of sensitivity, in the target prediction algorithm.
Variation in the primer sites was necessary to maintain specificity for each gene.
This important difference allows selection of ligands that maintain specificity for cancer cells by preventing nonselective membrane penetration.
Thus, restriction of lateral diffusion by endocytosis may serve to maintain specificity of syntaxin localization during late cytokinesis.
Biochemical regulatory motifs knows as insulating mechanisms are thought to have evolved to maintain specificity by limiting 'leaking' or 'spillover' or 'bleed-through' between pathways.
This manuscript describes a unique disintegrin-polymer fusion that maintains specificity for the disintegrin's target in vitro and in vivo.
Reported antigen MAL5 was recognized with IgA having 82.6% sensitivity with maintaining specificity up to 54.5% which is the best among all these specific antigens.
