Sentence examples for maintain repression from inspiring English sources

Thus, there are context-dependent mechanisms that selectively maintain repression of target gene transcription when the Notch pathway is activated.

Crosses and progeny were maintained at the non-restrictive temperature of 18°C to maintain repression of GAL4.

Thus, we conclude that specific binding of LHP1 to H3K27me3 is essential to maintain repression of PcG target genes.

This may reflect failure of repetitive element silencing in the absence of a localized XIST RNA signal, or failure to maintain repression of human repetitive elements in the somatic cell hybrid background.

Methylation of H3K9 is thought to function to maintain repression of the sex chromosomes in post-meiotic cells, in the absence of γH2AX [ 67].

Geminin has also been reported to bind to Polycomb group proteins, implying that it interacts with several chromatin modifiers to maintain repression of genes driving differentiation [ 46, 47].

Lodha, M., Marco, C. F. & Timmermans, M. C. P. The ASYMMETRIC LEAVES complex maintains repression of KNOX homeobox genes via direct recruitment of Polycomb-repressivecomplex2.

In normal skeletal muscle, where the PRC2 complex is highly expressed in muscle precursor cells and sharply downregulated upon differentiation19, this maintains repression of the antiproliferative TBX3 and expression of the proproliferative TBX2 when PRC2 is expressed.

Down-regulation of HvOS2 in vernalized plants is likely to contribute to accelerated flowering [47], and although HvOS2 is down-regulated by cold independently of VRN1, maintained repression of HvOS2 after vernalization requires VRN1 [47].

In embryonic stem cells, PcG proteins regulate stem cell pluripotency by maintaining repression of alternative lineage genes that are necessary for differentiation of stem or progenitor cells into various tissue types [35].

PTBP1 maintains repression of many exons in neuronal progenitor cells.