In samples with PTEN allelic loss 41% maintained protein expression.
To further highlight the importance of L29 in maintaining protein expression, we used mutagenesis and selection to obtain L29 variants that enhanced GFP expression.
Proliferating progeny of satellite cells, myoblasts, maintain Pax7 protein expression and upregulate the expression of MyoD, a muscle specific transcription factor.
The results demonstrated that periostin physically associated with the Notch1 precursor to maintain its protein expression level and affected the subsequent Notch signaling under a stress condition.
Fig 2C shows that IL-2, IL-15 and IL-7 are different in their ability to maintain Myc protein expression in effector CTL.
Furthermore, in wing and antennal discs ectopic Tsh can maintain Hth protein expression outside of its normal domain indicating a possible regulatory role for Tsh in Hth expression (Bessa et al., 2002; Bessa et al., 2009).
We have previously shown in normal tissues and tumours that cells arrested 'in cycle' can maintain MCM protein expression, designated as 'licensed' cells with proliferative potential (Stoeber et al, 2001; Dudderidge et al, 2005; Williams and Stoeber, 2007).
These data suggest for the first time that repeated treatments at 2-hour intervals with 10 μM HNE are essential to maintain the protein expression of COX-2 up to 24 hours.
For instance, the concentration of TGF-β (10ng/ml) used in our studies was insufficient on its own to maintain FoxP3 protein expression in the absence of exogenous IL-2 in vitro (Author response image 1), though it has been demonstrated to do so in other studies (Fantini, Nat Protocols, 2007).
