Sentence examples for maintain podocyte density from inspiring English sources

In summary, our study provides further evidence that MSCs can not only exert antialbuminuric effects but also prevent glomerular capillary occlusion and maintain podocyte density and foot process in the glomerular filtration barrier.

These findings implicate PECs as the means for normal glomerular growth, and are consistent with the idea that PECs serve to maintain podocyte numbers.

This result suggested that preserving K255E/WT Actn4 heterodimers from proteolysis might help to maintain podocyte function.

It has been shown that PI3K/AKT pathway related with SD molecules (SDs) is one key part of podocyte cell survival signaling to maintain podocyte functional integrity [ 28].

In contrast, administration of the antioxidant, α-lipoic acid was more effective in maintaining podocyte number and density.

In the healthy kidney, pinch and parvin may have an important role in transmitting signals from the extracellular matrix through integrin-linked kinase, to maintain podocytes in a differentiated state [ 43]. 2. Neuropilin and its interaction with the guidance molecule semaphorin have been implicated in podocyte differentiation [ 44, 45].

Hartleben, B. et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.

These findings highlight the importance of induced autophagy as a key homoeostatic mechanism for maintaining podocyte integrity.

However, some evidence indicates that SD maintains podocyte functional integrity not only because of foundation for the filter barrier but also participation in cell signaling such as PI3K/Akt [ 10].

SS-31 did not impact podocyte density, but it reduced markers of podocyte injury (desmin) and improved cytoskeletal integrity (synaptopodin).

Experimental diabetes resulted in a rapid decline in apparent podocyte number and podocyte density.