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Adjusting PEEP to maintain normal physiologic transpulmonary pressure is a reasonable premise.
In the study arm, PEEP was titrated to maintain normal physiologic transpulmonary pressure (0 to 10 cmH2O at end expiration).
Critically-ill patients (80%ARDS/20%% Acute Lung Injury) were randomized to either ARDS Network protocol ventilation or a ventilation strategy utilizing esophageal pressures to estimate individual patients' transpulmonary pressures and guide application of PEEP to maintain normal physiologic parameters.
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COX-1 is a housekeeping enzyme, constitutively expressed in most mammalian tissues, and it is responsible for maintaining normal cellular physiologic functions.
Using genetically engineered human skin tissue in vivo, we demonstrate that diminished, sub-physiologic expression of IQGAP1 or IQGAP3 is sufficient to maintain normal epidermal homeostasis, whereas significantly higher levels are required to support tumorigenesis.
Essential nutrients help maintain normal neuronal plasticity.
Cinnamon also helps maintain normal sugar levels.
Thus our findings in normal mucosa suggest a balanced production of MMP-2 and its inhibitors in order to maintain a normal physiologic condition.
At physiologic levels, E2 is thought to be involved in maintaining normal insulin sensitivity and to be beneficial for β-cell function (Livingstone and Collison 2002; Louet et al. 2004).
The tissue has a dynamic role in maintaining normal carbohydrate and lipid levels as well as in regulating metabolic and other physiologic functions.
Otherwise, they maintained normal social activity.
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