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To date, the primary role discovered for IL-23 is to maintain lymphocytes that secrete IL-17A, IL-17F, and IL-22 or to directly induce the production IL-22 [6], [6].
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The doses of DOX (5 mg/kg) and of PTX (25 mg/kg) used in our investigation are sufficiently low to maintain lymphocyte effector cell activity as demonstrated by the ability of the vaccines to induce antitumor immunity.
Tregs were originally identified because of their ability to prevent organ-specific autoimmune disease by maintaining lymphocyte homoeostasis and regulating activated T cells20.
This deletion process is crucial for maintaining lymphocyte homeostasis and the prevention of autoimmunity, for example, by limiting production of inflammatory cytokines.
Li, Y. et al. Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation.
Taken together, our results suggest that p53 is important to maintain CLL lymphocyte homeostasis following exposure to dasatinib and suggest that dasatinib may be effective to treat del 17p13.1 CLL patients.
Moreover, fasting can decrease the activities of both mucosal T and B cells in terms of their ability to maintain pulmonary lymphocyte populations and mucosal IgA secretion in the respiratory tract and intestinal mucosa [ 33, 34]; thus, immune dysfunction resulting from immunosenescence, hypoalbuminemia, or fasting may be associated with a prolonged length of stay in older patients.
Specific immune responses depend on extensive clonal expansion of specific T or B lymphocytes, and telomerase is very probably critical in securing immune function by maintaining the lymphocytes' replicative potential [43].
The ability to suppress T-cell responses to mitogenic and antigenic signals is explained by a complex mechanism of induction of "division arrest anergy", responsible for maintaining T lymphocytes in a quiescent state.
In addition, samples need to be carefully handled to maintain viability of lymphocytes.
Perhaps lymphocytes maintain high levels of transcripts encoding the translational apparatus in order to be ready to rapidly ramp up the capacity for protein synthesis when activated.
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