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This suggests that the mechanisms triggering and maintaining headache were operating for a longer period than the stress-induced peripheral and muscular mechanisms usually do.
In addition, neurogenic sensory vasodilatation may have also beneficial effects by removing tissue metabolites inducing, aggravating or maintaining headache attacks [19].
Besides psychological and genetic factors, several cross-sectional and prospective studies indicate that the family climate, school burden, as well as the number of life events also increase the probability of developing and maintaining headache [23 29].
All patients were asked to maintain a headache diary, in which details on the number of headaches and adverse events were recorded.
Between month 16 and month 37, two reprogramming sessions were required to maintain complete headache relief.
Patients were asked to maintain a headache diary for at least 30 days prior to and continuously after receiving OnabotulinumtoxinA treatment.
Each pregnant woman after 20 weeks of pregnancy suffering from a difficult-to-maintain headache should be examined for preeclampsia [120 124].
It is already defined that analgesic overuse is important to establish and maintain chronic headaches [21].
Each patient maintained a headache diary and completed standardized pain questionnaires before and after the therapy.
Patients were injected intramuscularly as per PREEMPT, and maintained a headache diary for 30 days before/after BOTOX treatment.
Adult patients with CM attending the Hull migraine clinic were offered Botox based on clinical needs and maintained a headache diary.
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