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For muscle to function properly throughout the process of E C coupling, the muscle fibers must maintain functional levels of Ca2+ within the SR.
The finite source of neurotrophins in experimental (pump-based) delivery systems that eventually require replacement has led to increased interest in the use of gene therapy to maintain functional levels of acoustic hearing.
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Though speculative, it is possible that strong promoters may be able to tolerate mutations that result in moderately reduced or increased activity, because their transcriptional activity would still be sufficient to maintain functional expression levels.
Our data indicated that EZH2 was released with a concomitant decrease in H3K27me3 at the PPARγ promoter on Day 1, and by Day 5, both EZH2 and H3K27me3 were reestablished, likely to maintain functional PPARγ level after neuron differentiation (Figs 4B and S4).
In fact, hormone-refractory prostate cancer cells often can maintain functional AR signaling despite greatly reduced levels of circulating testosterone as, for instance, with orchiectomy (Deutsch et al. 2004) because of AR overexpression.
Using the best available scientific evidence [ 7, 8], public health messages from the Centers for Disease Control [ 9] and the National Institute on Aging [ 10] encourage older persons to increase physical activity levels in order to maintain functional independence.
Here we show that the apoptosis inhibition provided by the Apaf1 inhibitor SVT016426 at the level of apoptosome contributes to maintain functional cells, thus raising hope for the development of future treatments of unwanted pathological apoptosis.
Maintaining muscle function is vital to maintain functional independence.
Being an ambassador is about working to maintain functional relationships.
It helps them to maintain functional ability to some extent.
All participants described the importance of maintaining functional capacity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com