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The corresponding inward convection of flux tubes must have been elevated to maintain flux conservation.
The macro equivalent current density J, which is composed of eddy currents to maintain flux quantum beam in the numerous flux pinning centers, was enhanced with increase of the initial captured flux.
It is also possible that the catabolic pathways activated upon sucrose starvation at 80 and 100 h were suppressed in elicitor-treated cells to maintain flux into secondary metabolism.
It is of note that although FA biosynthesis enzymes were transcriptionally downregulated, their absolute abundance remained relatively high at this stage, ranging from a minimum value of 3 FPKM for KAS3 to 572 FPKM for ACP2, presumably to maintain flux towards FA biosynthesis (Fig. 2c).
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However, the reconstruction of these complex biosynthetic schemes faces numerous challenges due to the number of enzymatic steps and challenging enzyme classes associated with these pathways, which can lead to issues in metabolic load, pathway specificity, and maintaining flux to desired products.
The GIMME (Gene Inactivity Moderated by Metabolism and Expression) algorithm, proposed by Becker and Palsson [ 14], maintains flux through a proposed metabolic objective (similar to FBA) by simultaneously punishing flux through unexpressed reactions.
In contrast, S. coelicolor encodes another UrtR homologue, TamR, which is responsible for regulating the activity of genes encoding proteins involved in maintaining flux through the citric acid cycle: DNA binding by TamR is attenuated by trans-aconitate and closely related compounds but not by urate.
Enrichment in foam fractionation is enhanced by reducing the liquid flux while maintaining the flux of bubble surfaces.
Many microfiltration systems are now run at constant filtrate flux to achieve improved performance; however, large increases in transmembrane pressure are often required to maintain the flux at a constant value due to membrane fouling.
To maintain high flux for membrane applications, elastic recovery and thermal treatment proved beneficial in reversing the effects of uniaxial orientation on PEBA copolymers.
Transgenic CKM overexpressing mice were found to maintain CK flux at higher levels in a heart failure model of pressure overload, associated with higher ejection fraction and improved survival [112].
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