Sentence examples for maintain efficacy and from inspiring English sources

Importantly, unlike bleeding, efficacy did not change across the AM exposure range; thus dose reduction should maintain efficacy and reduce bleeding [ 74].

An open-label, multiple-dose, crossover study carried out in 85 patients aged 3 18 years, nevirapine XR exhibited pharmacokinetic profiles that provided adequate geometric trough levels to maintain efficacy and was well tolerated.

Lower doses of irinotecan and adding other chemotherapeutic agents such as cis-platin to the regimen would be indicated to treat these cancer patients to maintain efficacy and reduced side effects.

Thus, MPH needs to be taken repeatedly throughout the day in order to maintain efficacy, and this can lead to adherence issues and additional complications if the drug needs to be taken during school hours [ 16].

The goal of modern smaller field radiation therapy is to reduce both treatment volume and treatment dose while maintaining efficacy and minimizing acute and late sequelae.

Any developments in treatment are therefore being directed towards maintaining efficacy and reducing toxicity.

As illustrated in Figure 1, the Kaplan Meier curves separated during the first day, maintaining efficacy, and continued to separate throughout the 450-day follow-up period.

This open-label, randomized study in 324 stable kidney transplant recipients demonstrated that patients can be successfully converted from tacrolimus twice daily to LCPT, while maintaining efficacy and safety.

Combinatorial treatments might lead to synergistic effects on growth control or induction of apoptosis, thereby allowing the use of lower concentrations as well as maintaining efficacy and reducing side effects.

Among patients who were dose-reduced to edoxaban 30 mg once daily, the rates of VTE recurrence, major bleeding and major or CRNM bleeding were all lower in the edoxaban group than in the warfarin group, suggesting that patient-specific dosing of edoxaban maintains efficacy and safety [ 33].

To confirm that EC154 and LBH589 similarly maintain efficacy under hypoxia, UMCRC2 and 786-O cells were exposed to hypoxia [ 25, 71] for 16 h in either the presence or absence of these agents.