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How do matricellular proteins maintain dormant tumor cells in a quiescent state or reactivate them to metastatic outgrowth?
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"Maersk Line will maintain a dormant business entity in Iran and will look to resume business should the sanctions regime be eased," the spokesperson concluded.
Actively growing HeLa cells maintain a dormant p53 pathway and elevated telomerase activities [ 49].
However, to date, few miRNAs that maintain the dormant or active state of DTCs have been identified.
Seeds were harvested at 40 d after flowering and air-dried in the greenhouse for 3 d before storage in a −20° freezer to maintain the dormant status.
HeLa cells maintain a dormant p53 pathway and elevated telomerase activity resulting from HPV-mediated transformation, whereas TTP expression counteracted this effect by stabilizing p53 protein and inhibiting hTERT expression.
Nevertheless, the immune system remains actively involved in every step of cancer progression, including during the phase of dormancy; for instance, CD8+ T cells maintain the dormant status in preclinical cancer models [ 16].
The stem cell niche could therefore play a central role in maintaining a dormant pool of HSC to prevent replicative senescence over the lifetime of the organism [62].
The regulatory role of small RNAs in repression of gene expression could potentially provide an important mechanism in establishing or maintaining the dormant state in grain or altering storage reserves.
We suppose that genes may be involved in maintaining the dormant state.
We suppose that those genes may be involved in maintaining the dormant state.
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CEO of Professional Science Editing for Scientists @ prosciediting.com