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The use of currently available, nonspecific, systemic immunosuppressive therapies for patients with moderate to severe psoriasis is limited by an inability to maintain disease remission safely.
Palliative or non-curative treatment intent was defined as patients with no further active treatment options available, but those that could be on phase 1 trials or be receiving treatment to control or maintain disease stability but without curative intent.
The Wegener's Granulomatosis Etanercept Trial (WGET) is a randomized, double-masked, placebo-controlled trial designed to test the ability of etanercept, a soluble inhibitor of tumor necrosis factor, to maintain disease remission when used with conventional treatments.
Given the worldwide expansion of bombiculture, it is imperative that commercial rearing facilities work to achieve and maintain disease free bumble bees for crop pollination.
Consequently, the majority of people with psoriasis require long-term treatment to maintain disease control.
Interestingly, several patients on both treatments appeared to maintain disease control after crossover.
Similar(30)
"By plowing and not adding residues back in, they were destroying the food web, which wasn't holding on to nutrients or maintaining disease suppression," Dr. Ingham said.
But the illusion of AIDS as a chronic but easily maintained disease that is no longer fatal has given rise to more casual unsafe sex, and increases of infections among young and even middle-aged gay men.
Dr. Steven Galson, director of the Center for Drug Evaluation and Research, part of the Food and Drug Administration, said, "Remicade is not a cure, but it provides a much-needed option for reducing the symptoms and inducing and maintaining disease remission in children who have no other safe and effective therapy".
The available studies have indicated that resective surgery (i.e. apical re-positioned flap + bone contouring) + implantoplasty was more effective in obtaining and maintaining disease resolution over resective surgery alone [42, 57].
However, most patients experience periodic disease flares, so maintaining disease control remains a challenge.
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CEO of Professional Science Editing for Scientists @ prosciediting.com