Sentence examples for maintain cell survival from inspiring English sources

Early UPR responses attenuate protein synthesis, promoting adaptive responses to restore ER function and to maintain cell survival.

However, Shh functions cell-autonomously to maintain cell survival in the dermomyotome and promote slow muscle differentiation.

Cancer cells lacking constitutively active Akt are able to induce sufficient AMPK-dependent β-oxidation following glucose restriction to maintain cell survival.

Stimulation of fatty acid oxidation was sufficient to maintain cell survival as activation of fatty acid oxidation with bezafibrate also protected Akt-expressing cells from glucose withdrawal-induced death.

In turn trophic factors, such as bFGF, may be needed to maintain cell survival in face of this increased stress.

Nevertheless, it still remains to be clarified how BCR and BAFF-R signals act on one another and are integrated within the cell to maintain cell survival.

Mechanistically, MEIS1 drives MPNST cell growth via the transcription factor ID1, thereby suppressing expression of the cell cycle inhibitor p27Kip and maintaining cell survival.

The proteasome is involved in degradation of numerous proteins which regulate the cell cycle, indicating a role in controlling cell proliferation and maintaining cell survival.

In hydrogel scaffolds for 3D cell culture, porous structure plays a central role in maintaining cell survival by delivery of biochemical factors through the scaffolds.

The UPR maintains cell survival by limiting cell proliferation and further accumulation of unfolded or misfolded proteins in ER.

For example, EGFR forms a heterodimeric complex with ErbB3, which binds to and directly activates phosphatidylinositol 3-kinase and maintains cell survival through AKT-dependent mechanisms [12].