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Such a relationship among ion channel mRNA levels may result from homeostatic mechanisms designed to maintain cell activity despite perturbations [13] [20].
MMP alterations lead to changes in cellular ATP production, which supplies energy to maintain cell activity.
The reason for the decreased xylose utilization rate in late stationary phase (after ~40 h) is unknown; it could be due to cell aging, synergistic effects of end products (such as ethanol) with other inhibitors in the media, insufficiency of ATP synthesis to maintain cell activity, or redox imbalance during xylose metabolism.
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Taken together, our results identify the critical role of the HES6 transcription co-factor in maintaining AR activity in CRPC with concerted enhancement of E2F1 activity to maintain cell growth in the absence of testosterone and thereby offer a fresh treatment paradigm in combating this disease.
This family is not well characterised functionally, but some members use their hydrolase activity to maintain cell homeostasis and have been implied to play a role in plant defence.
This implies that at least one of the pathways that normally maintain cell integrity cannot function without AMPK activity.
Our data indicate that the N-terminus domain of Vps15 containing the myristoylation signal for membrane localization and the putative catalytic domain is required to regulate Vps34 stability and PI3K activity, and to maintain cell viability.
These results proved that ERE-D20 maintained cell adhesion activity, even after fusion with D20.
High levels of β-Catenin maintain cells pluripotent but this activity is not stable.
Accordingly, maintaining the balance between auxin and cytokinin is a key feature of plant stem cell regulation, both to maintain stem cell activity and to define the functional domains guiding stem cell differentiation.
Moreover, the Lgr5+ cell population within existing intestinal adenomas maintain stem cell activity and fuels the growth of the tumor [ 13].
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