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We have shown that blowing cooled air produced by a vortex tube into the nasal cavities is an effective and safe method to selectively reduce and maintain brain temperature on ten normal juvenile pigs.
In this study, we investigated whether blowing cooled air (−5 to 16 °C) produced by a vortex tube into the nasal cavities is an effective cooling method to selectively reduce and maintain brain temperature over an extended period of time before gradually returning to the baseline temperature on normal juvenile pigs.
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Therefore adequate glucose supply is crucial to maintain brain function.
Maintaining the brain temperature within certain limits is critical for animals; to assist this, dromedaries have a rete mirabile, a complex of arteries and veins lying very close to each other which uses countercurrent blood flow to cool blood flowing to the brain.
Fischer and colleagues [ 11] maintained the brain temperature of seven patients at 36.5°C as a form of prophylactic normothermia.
Billions of neurons maintain brains electric charge.
Maintaining brain Cu homeostasis is vital for normal brain function.
This study investigated whether blowing cooled air from a vortex tube into the nasal cavities is safe and effective to selectively reduce and maintain before slowly rewarming brain temperature back to normal temperature.
Brain temperature was maintained at 37.5 ± 0.5 °C and rectal temperature is decreased to 28 ± 0.5 °C during CA. Mechanical ventilation was restarted 30 seconds before CPR and CPR, chest compression and epinephrine administration, was initiated at 8 minutes after CA onset.
Brain temperature was maintained between 35.0 and 36.0°C using cooling blankets or an intravenous cooling system (Intravascular Temperature Management: IVTM™, Alsius® Irvine, CA, USA).
Brain temperature was maintained between 35 and 36.0°C using cooling blankets or an intravenous cooling system (CoolGard3000; Alsius; 15770 Laguna Canyon Road, Suite 150, Irvine, CA, USA).
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