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Subjects were instructed not to disclose any information about the intervention to maintain blind conditions.
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The lithium and placebo capsules were identical in appearance, smell, and taste to maintain blinding.
The single-dose group received an infusion of gentamicin and clindamycin, followed by an administration of intravenous placebo 8 and 16 hours later to maintain blinding.
Patients received ibandronate IV injections 2 mg every 2 months, 3 mg every 3 months or oral ibandronate 2.5 mg daily, plus oral or IV placebo, as appropriate to maintain blinding.
Matching placebos were administered to maintain blinding.
Instructions were also given to the referent member to maintain blinding during the telephone interview.
Results were monitored by an independent physician to maintain blinding of the clinical study team.
The delivery volumes of the vaccines with and without CPG 7909 were slightly different (0.55 and 0.50 mL respectively), so opaque tape was used to mask the contents and maintain blinding by the person administering vaccines.
At the recommendation of the DSMB, the randomisation and labelling process was audited halfway through the study by an independent observer and found to be robust, accurate and able to maintain blinding of other study staff and participants.
Sitagliptin and glipizide matching placebos were used to maintain blinding.
Pancreatin and placebo capsules were identical to maintain blinding.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com