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Although transcribed, EST library derived SSR loci still maintain allelic variability comparable to that in non-transcribed genomic DNA [ 30] and serve as excellent molecular markers for many applications [ 31].
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Such alleles could maintain allelic diversity in different varieties and enlarge the allele difference in the rice germplasm.
They could be polymorphisms that are maintained in populations by processes similar to those that maintain allelic polymorphisms [ 30].
This approach would maintain allelic diversity and guarantee a more effective response to selection while controlling inbreeding [ 61, 64].
Thus, the cells we studied maintained allelic exclusion.
In particular, pathogens have been long suspected to be responsible for maintaining allelic variation at the MHC [ 6].
Regarding allelic variability, the C alleles at both IL6 and IL1B SNPs were significantly more frequent in the infected than in the uninfected cases (p ≤ 0.050).
An alternative species concept is the stable ecotype in which cohesion of bacterial strains of a given species is maintained by accumulation of advantageous mutations and periodic purging of allelic variability [ 9].
To shed light on the origin of p1 allelic variability, we analyzed here three p1 alleles in their chromosomal context, namely p1-ww[4Co63] p1-ww[4Co63]d P1-rr4B27.
Different VNTR loci showed different ranges of allelic variability (Table 1).
This same pattern was mirrored across the distribution in California, where Sierra Nevada and Bay Area populations had lower allelic variability compared to those previously studied in coastal southern California.
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