Specifically, it has been demonstrated that loss of histone H3K9, H3K27, and H4K20 trimethylation markedly impairs chromatin structure, diminishes the ability of the cells to regulate and maintain accurately the cell cycle, disrupts the balance between cell proliferation and differentiation, and severely reduces cell viability (Rea et al. 2000; Yang and Mizzen 2009).
By the addition of alkaline substrate throughout the fed-batch phase, the pH was maintained accurately at 6.0 ± 0.1 (Fig. 2a,b).
A fairly easy case falls under a federal securities law provision that requires JPMorgan to maintain records to "accurately and fairly reflect the transactions and dispositions of the assets of the issuer".
To maintain the cells accurately and consistently in the center, a special chamber consisting of two cover plates, attached to a bottom plate [ 23], was used to allow slide insertion without wiping off the cell layer.
This format has inherent limitations with respect to maintaining and accurately recording unique identifiers that can link patients across the different clinics (antenatal, delivery, child), and also poses challenges when compiling aggregate data.
The fitness of the world's best team made the difference because they were able to keep clear minds, execute accurately and maintain their thought processes.
This enables the user to accurately maintain the data and refer back to its source if necessary at a later date.
We hypothesise that the massed practice group will show a higher task-related theta power than the distributed practice group towards the end of the practice, reflecting a higher cognitive load and increased effort to maintain attention and perform accurately [ 4, 21- 27].
However, the most important and challenging task in designing HIS is to organize and maintain patient information repositories securely, accurately and in speedy manner.
We encountered difficulty in motivating patients to accurately and punctually maintain a diary of clinical events.
