Sentence examples for maintain a repressive from inspiring English sources

BAHD1 is overexpressed in peripheral blood mononuclear cells and pancreas, and excels critical function to maintain a repressive state of interferon-stimulated genes and insulin-like growth factors (Bierne, Tham et al. 2009, Lebreton, Lakisic et al. 2011).

The data suggest that LSD1 and HDACs cooperate to maintain a repressive state of the hTERT transcription in normal human MRC5 cells.

Thus, CBF has an effect on the chromatin structure of three early target genes of MyoD and contributes to maintain a repressive chromatin state.

In this model system, the introduction of H3K9me2 is the consequence of the binding of the receptor along with the histone methyltransferase to maintain a repressive environment.

Evidence exists to suggest that DNA methylation and histone deacetylation interact to maintain a repressive chromatin complex at the ER promoter.

Previous studies of individual genes have shown that in a self-enforcing way, dimethylation at histone 3 lysine 9 (dimethyl-H3K9) and DNA methylation cooperate to maintain a repressive mode of inactive genes.

For instance, he's backed a more active Saudi role in combatting the Islamic State -- which raises eyebrows among progressives, given the Saudi role in Yemen, spreading religious extremism, and maintaining a repressive theocracy at home.

While Carrington succeeded in keeping the state secure, his operatives also carried out arbitrary arrests, suppressed freedom of speech and freedom of association, and generally maintained a repressive control of the southern-sympathetic minority.

MES-4 is therefore not required for the H3K4me erasure mechanism in early PGCs, but is important for maintaining a repressive chromatin state in these cells.

Taken together, our previous studies and the present findings suggest that RFX1 restricts the expression of CD11a and CD70 and possibly other autoimmune-related genes by maintaining a repressive chromatin state of their promoters.

These data supported the model that the expanded GAA repeat structure induces and/or maintains a repressive heterochromatin structure, which is generally thought to inhibit access of transcription factors and thus leads to transcriptional silencing of the respective gene (Dion & Wilson, 2009; Pandolfo, 2009).