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We show that the physiological function of Kir7.1 is to maintain a hyperpolarized membrane potential during uterine quiescence and that removal of this hyperpolarizing drive renders the uterus more excitable.
TASK-2 channels are hypothesized to maintain a hyperpolarized condition of retrotrapezoid nucleus neurons, thereby preventing a respiratory increase at low CO2 partial pressure [17].
Their strong inward and outward rectifications make it difficult for them to maintain firing during depolarization and also to maintain a hyperpolarized state [17] [19], [60].
It is known that KCNN4 channels in lymphocytes can maintain a hyperpolarized membrane potential, thereby facilitating and maintaining the intracellular Ca2+ levels required for cell proliferation and gene expression [ 27, 28].
At low glucose concentrations and low ATP/ADP ratios, the channel is open, allowing K+ ions to flow out of the cell along their concentration gradient to maintain a hyperpolarized membrane potential of between −65 and −53 mV [ 48].
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maintain a white background.
Maintaining a Balance.
Furthermore, the oxygen and ATP consumption is approximately 50% greater in the dark than in the light because photoreceptors need to be maintained in the hyperpolarized state until they are depolarized in response to light (Kimble et al. 1980).
Membrane potentials were maintained at −70 mV, and voltage steps were delivered from a hyperpolarized potential of −100 mV to −110 mV and subsequently depolarized with 10 mV steps up to either 10 mV or 80 mV at a rate of 1 Hz for up to seven repetitions.
In this paper, we present a new dynamic chemical-shift imaging method that uses specialized RF pulses designed to maintain most of the hyperpolarized substrate while providing adequate SNR for the metabolic products.
Moreover, voltage-dependent activation and steady-state inactivation curves of Nav1.8 were shifted in a hyperpolarized direction.
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