If the results show refractory CSE or progression to NCSE, the patient is given a 2-mg/kg propofol bolus, repeated every 5 min if necessary, and then a maintenance intravenous infusion at 2 5 mg/kg/h to obtain and maintain a burst-suppression EEG pattern for 24 h.
Ketamine* 1 3 mg/kg IV bolus, followed by a continuous IV infusion at a dose sufficient to maintain a burst-suppression pattern on the EEG (usually up to 5 mg/kg/h).
OR Pentobarbital 5 15 mg/kg IV bolus, followed by a continuous IV infusion at a dose sufficient to maintain a burst-suppression pattern on the EEG (usually 0.5 3 mg/kg/h).
rate of 4 mg/min initially, followed by a continuous IV infusion at a dose sufficient to maintain a burst-suppression pattern on the EEG (usually 0.05 0.4 mg/kg/h).
Consider the use of: Ketamine* 1 3 mg/kg IV bolus, followed by a continuous IV infusion at a dose sufficient to maintain a burst-suppression pattern on the EEG (usually up to 5 mg/kg/h).
The following drugs need to be administered by a neurointensivist/experienced anaesthetist in an intensive care unit setting: Propofol 2 mg/kg IV bolus infusion, repeated if necessary, and then followed by a continuous infusion of 5 10 mg/kg/h initially, reducing to a dose sufficient to maintain a burst-suppression pattern on the EEG (usually 1 3 mg/kg/h).
Propofol 2 mg/kg IV bolus infusion, repeated if necessary, and then followed by a continuous infusion of 5 10 mg/kg/h initially, reducing to a dose sufficient to maintain a burst-suppression pattern on the EEG (usually 1 3 mg/kg/h).
OR Thiopental 100 250 mg IV bolus infusion giver over 20 s with further 50-mg boluses every 2 3 min until seizure control, followed by a continuous IV infusion at a dose sufficient to maintain a burst-suppression pattern on the EEG (usually 3 5 mg/kg/h).
A basic rule in the middle distance races (800 and 1600-meters) is that a runner must maintain a fast pace and maintain enough energy to have two bursts of acceleration.
Therefore, a slender body but a similar peduncle depth in comparison with the normal species could represent a trade-off to minimize the costs of foraging and predation risk and maintain adequate burst and prolonged swimming capacities.
