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As tends to be the case, the momentarily convenient term became an imprisoning category, with mainstream used to corral poets who wrote for the page rather than performance, and whose work was not self-consciously avant-garde.
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Unsurprisingly, the most mainstream use of nanotextiles is in clothing.
To date, holographic storage has not been on a path to mainstream use.
To enter mainstream use, any such treatment typically needs to clear a high bar.
The Pew report notes how quickly technologies like these can go from obscurity to mainstream use.
But some entrepreneurs, investors and even merchants are eyeing a far more mainstream use for it.
Health Minister Jillian Skinner said it could take years for the trials to be approved for mainstream use.
One network, PAPNET, is already gaining mainstream use in the screening of digitized Pap smears for cancer.
"I always felt that voice recognition was a technology that would someday be applied to mainstream uses," he says.
There is a science much underused in the UK – yet in mainstream use elsewhere in the world – that might perhaps have helped.
Although Google's self-driving cars have been a technological success the search-giant has had difficulty finding a method of getting the vehicles into mainstream use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com