Sentence examples for mainly unsolved from inspiring English sources

With the delivery to most organs mainly unsolved, there is so far no approved siRNA-based clinical treatment, whereas two FDA-approved gapmers have reached the clinic for the treatment of CMV retinitis and severe hypercholesterolaemia, respectively.

Most authors agree that this lack of definitive experimental evidence is mainly due to unsolved technical issues of the assay.

Although the problem of acquired drug resistance has classically been studied in vitro, drug resistance in vivo is still unsolved, mainly because these drug-resistant models lack consideration of the role of the tumor microenvironment.

Despite the substantial progression in understanding WBD, many questions remain unsolved, mainly those concerning the mechanisms controlling processes such as: (i) the fungal switch from biotrophism to saprotrophism; (ii) the drastic phenotypic alteration of cacao during disease development and (iii) the death of infected tissues.

In "Casting JonBenet," Green relies on the formalized settings of on-camera auditions to interview a batch of largely nonprofessional, mainly inexperienced actors about the unsolved killing of JonBenét Ramsey.

In spite of all the research efforts in this area, there are still unsolved issues concerning VoIP calls, mainly caused by the specific wireless network characteristics.

Scale-up of a crystallizer is an extremely difficult and unsolved issue up till now, mainly because of the complexity of occurring phenomena from kinetic and fluid-dynamics point of view.

However, two unsolved problems remained, and they were mainly answered in this study.

In addition some legal issues, mainly regarding liability, and issues related to patient privacy and patient safety, as yet remain unsolved [21].

Mystery unsolved.

Both murders remain unsolved.