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In its recombinant form (Rec), mainly two isoforms have been assayed: RecEgAgB1 and RecEgAgB2.
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It exists mainly in two isoforms COX-1 and COX-2 [A.
Estrogen exerts its neuroprotective effects through various ERs, which consist mainly of the two isoforms, ERα and ERβ.
We conclude that the two isoforms mainly differentiated in term of regulation, keeping a similar function of NF-κB activation.
SK exist as two isoforms, SK1 mainly found in the cytoplasm and SK2 found in the nucleus.
p63 has central roles in epithelial development and despite the two isoforms share some common features, TAp63 mainly acts as tumor suppressor and ΔNp63 as an oncogene.
Recent studies have identified two isoforms of the TpH enzyme, TpH1, which is present in mainly peripheral organs such as the gut, and TpH2, which is associated with the nervous system and present predominantly in the brain stem.
The two isoforms share the same primary structure, but differ in the secondary; PrPSc consists mainly of β-pleated sheet [2], while PrPC contains a two-stranded antiparallel beta-sheet and three alpha-helices [3], [4].
Differential splicing generates two isoforms, M1 or M2.
In humans, CGRP is present in two isoforms, α-CGRP and β-CGRP, where α-CGRP is most abundantly found in primary spinal afferents from sensory ganglia, whereas β-CGRP is mainly found in the enteric nervous system [6].
MAP6 transcripts are expressed as two isoforms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com