Sentence examples for mainly target cells from inspiring English sources

T lymphocyte cells mainly target cells of the body that have been invaded by pathogens such as viruses, or that show abnormal molecular patterns on their surface associated with cancerous growth or necrosis.

Further, harnessing breakthrough and targeting cures in human ovarian cancer requires insightful understanding of the merits and drawbacks of current treatment modalities, which mainly target transformed cells.

Conventional chemotherapeutic agents mainly target malignant cells by either inducing DNA damage or blocking DNA replication.

Therefore it is likely that PPARgamma ligands mainly target TH1 cells in our model to mediate their anti-inflammatory action.

Unlike dose-dense chemotherapy, which mostly targets proliferating tumor cells, frequent or continuous metronomic chemotherapy mainly targets endothelial cells [ 6].

Upon therapeutic genotoxicity that mainly targets cancer cells, which are in active phases of turnaround and proliferation, cells within the TMEN have several responses.

Instead, IL-22 mainly targets epithelial cells which express high levels of IL-22R1 [ 1– 6].

Chronic and frequent treatment schedules have been reported as the most appropriate to exploit the antiangiogenic effect of cytotoxic drugs, compared to the high-dose/intermittent-schedule mainly targeting tumour cells (Hanahan et al, 2000; Miller et al, 2001).

We describe here the gross and histopathological lesions associated with acute metallic phosphide exposure in a dog, showing that the toxic is mainly responsible for systemic acute necrotizing and hemorrhagic type of lesions, mainly targeting endothelial cells with secondary ischemic necrosis in the affected tissues.

These cells mainly target distal tufts of pyramidal cells (Kawaguchi and Kondo 2002; Silberberg and Markram 2007) and have been shown to express nAChRs in layer V (Couey et al. 2007).

Decreased responsiveness to chemotherapy might be due in part to the slow proliferation rates of CSCs, given that conventional cytotoxic drugs mainly target highly proliferative cells [ 15].